The cognitive phenotypes of Creutzfeldt-Jakob disease: comparison with secondary metabolic encephalopathy.

Anna Rita Giovagnoli Giuseppe Di Fede Giacomina Rossi Fabio Moda Marina Grisoli Orso Bugiani

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2022)

In CJD, clinical and neuropsychological analyses outline a salient cognitive phenotype suggestive of fronto-temporal dysfunction preceding severe dementia. This phenotype is different from that observed in other rapidly progressive encephalopathies.

Keyphrases

mild cognitive impairment
early onset
multiple sclerosis
oxidative stress
cognitive impairment