Development and validation of an ultra-performance liquid chromatography-tandem mass spectrometric method for the determination of 25 psychoactive drugs in cerumen and its application to real postmortem samples.

Orthodoxia MastrogianniAmvrosios OrfanidisEvdokia BrousaDimitrios-Phaedon KevrekidisHeleni ZagelidouNikolaos Raikos

Published in: Forensic toxicology (2022)

According to our knowledge, it is the first time that a method for the simultaneous detection of 25 psychoactive drugs in cerumen was developed, fully validated and finally applied to 25 postmortem samples.

Keyphrases

liquid chromatography
mass spectrometry
healthcare
solid phase extraction
high resolution mass spectrometry
high resolution
tandem mass spectrometry
simultaneous determination
drug induced
molecularly imprinted
label free
real time pcr