LncRNA Uc003xsl.1-Mediated Activation of the NFκB/IL8 Axis Promotes Progression of Triple-Negative Breast Cancer.

Ying XuWei RenQingjian LiChaohui DuanXiaorong LinZhuo-Fei BiKaiyun YouQian HuNing XieYunfang YuXiaoding XuHai HuHerui Yao

Published in: Cancer research (2022)

These findings identify an epigenetic-driven NFκB/IL8 cascade initiated by a lncRNA, whose aberrant activation contributes to tumor metastasis and poor survival in patients with triple-negative breast cancer.

Keyphrases

signaling pathway
lps induced
pi k akt
long non coding rna
nuclear factor
oxidative stress
dna methylation
long noncoding rna
gene expression
cell proliferation