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MGCD0103, a selective histone deacetylase inhibitor, coameliorates oligomeric Aβ25-35 -induced anxiety and cognitive deficits in a mouse model.

Hei-Jen HuangHsin-Yu HuangHsiu Mei Hsieh-Li
Published in: CNS neuroscience & therapeutics (2018)
These results reveal MGCD0103 could be a potential therapeutic agent against AD.
Keyphrases
  • histone deacetylase
  • mouse model
  • high glucose
  • diabetic rats
  • genome wide
  • single cell
  • sleep quality
  • drug induced
  • endothelial cells
  • oxidative stress
  • physical activity
  • depressive symptoms