The aggravation of arthritis by periodontitis is dependent of IL-17 receptor A activation.

Sabrina Garcia de AquinoJhimmy TalbotFabiane SônegoWalter M TuratoRenata GrespanMario J Avila-CamposFernando Q CunhaJoni A Cirelli

Published in: Journal of clinical periodontology (2017)

The effects of P. gingivalis-induced periodontitis on arthritis are dependent on Th17 expansion and IL-17RA signalling, which lead to increased neutrophil infiltration into the joints.

Keyphrases

rheumatoid arthritis
high glucose
disease activity
diabetic rats
ankylosing spondylitis
drug induced
interstitial lung disease
systemic lupus erythematosus
endothelial cells
binding protein