Rhamnolipid-coated W/O/W double emulsion nanoparticles for efficient delivery of doxorubicin/erlotinib and combination chemotherapy.

Yeeun LeeDonghyun LeeEunyoung ParkSeok-Young JangSeo Young CheonSeongryeong HanHeebeom Koo

Published in: Journal of nanobiotechnology (2021)

The developed RL-NP-DOX-ERL provided efficient delivery of DOX and ERL to tumor tissue and successful tumor therapy with a synergetic effect. Importantly, this study demonstrated the promising potential of double-emulsion NPs and RL coating for combination therapy.

Keyphrases

combination therapy
epidermal growth factor receptor
squamous cell carcinoma
locally advanced
mesenchymal stem cells
risk assessment
climate change
rectal cancer