Anti-cancer therapy is associated with long-term epigenomic changes in childhood cancer survivors.
Natassia RobinsonJohn CasementMarc J GunterInge HuybrechtsAntonio AgudoMiguel Rodríguez BarrancoFabian EichelmannTheron JohnsonRudolf KaaksValeria Maria PalaSalvatore PanicoTorkjel M SandangerMatthias B SchultzeRuth C TravisRosario TuminoPaolo VineisElisabete WeiderpassRoderick SkinnerLinda SharpJill A McKayGordon StrathdeePublished in: British journal of cancer (2022)
These novel methylation changes could serve as biomarkers for assessing normal cell toxicity in ongoing treatments and predicting long-term health outcomes in CCS.