Efficacy and safety of low-dose imatinib in an elderly patient with mixed phenotype acute leukemia with t(9;22)(q34;q11.2);BCR-ABL1.

Yusuke OkayamaTeruhito TakakuwaIppei OtomaruMirei HoriuchiAkiko MiuraTaku ArakiYotaro FujitaniRyosuke Yamamura

Published in: Clinical case reports (2021)

Low-dose imatinib with monitoring of drug concentrations in blood may successfully control Philadelphia chromosome-positive mixed phenotype acute leukemia (Ph+MPAL), particularly in elderly patients with comorbidities.

Keyphrases

chronic myeloid leukemia
low dose
middle aged
high dose
community dwelling
case report
acute lymphoblastic leukemia
gene expression
emergency department
tyrosine kinase
drug induced
dna methylation