Correlation between genetic and environmental risk factors for age-related macular degeneration in Brazilian patients.

Priscila Hae Hyun RimJosé Paulo C de VasconcellosMônica B de MeloFlavio M C MedinaDaniela P D SacconiTamires P LanaFabio E HirataLuis A MagnaAntonia P Marques-de-Faria

Published in: PloS one (2022)

The analysis correlating environmental and genetic risk factors such as family history of AMD, and CVD and the variants of HTRA1, CFH, and LOC387715 genes showed an expressive contribution for the development of AMD among this admixed population.

Keyphrases

age related macular degeneration
genome wide
risk factors
end stage renal disease
copy number
ejection fraction
chronic kidney disease
peritoneal dialysis
human health
dna methylation
gene expression
life cycle
patient reported outcomes
bioinformatics analysis