The ecological effects of selective decontamination of the digestive tract (SDD) on antimicrobial resistance: a 21-year longitudinal single-centre study.

Sophie BuitinckRogier JansenSaskia RijkenbergJos P J WesterRob J BosmanNardo J M van der MeerPeter H J van der Voort

Published in: Critical care (London, England) (2019)

During more than 21-year SDD, the incidence rates of resistant microbes at the ICU level did not significantly increase over time but the background resistance rates increased. An overall ecological effect of prolonged application of SDD by counting resistant microorganisms in the ICU was not shown in a country with relatively low rates of resistant microorganisms.

Keyphrases

antimicrobial resistance
intensive care unit
climate change
mechanical ventilation
human health
risk factors
risk assessment
acute respiratory distress syndrome