Opioid-Associated Anorectal Dysfunction in Chronic Constipation.

Nayna A LodhiaLaura HortonNamisha ThapaAlison H GoldinWalter Wai-Yip Chan

Published in: Digestive diseases and sciences (2021)

Recent opioid use was an independent risk factor for rectal hyposensitivity and DD on HRAM in patients with constipation, but that effect may decrease with discontinuation of use. Anorectal physiology testing should be considered in patients with opioid-associated constipation.

Keyphrases

irritable bowel syndrome
chronic pain
pain management
oxidative stress
abdominal pain
drug induced