Decrements of body mass index are associated with poor outcomes of idiopathic pulmonary fibrosis patients.
Tejaswini KulkarniKaiyu YuanThi K Tran-NguyenYoung-Il KimJoao A de AndradeTracy LuckhardtVincent G ValentineDaniel J KassSteven R DuncanPublished in: PloS one (2019)
IPF patients with greatest BMI decrements had worse outcomes, and this effect persisted after lung transplantation. Weight loss in these patients is a harbinger of poor prognoses, and may reflect an underlying systemic process, such as adaptive immune activation.
Keyphrases
- idiopathic pulmonary fibrosis
- body mass index
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- type diabetes
- adipose tissue
- bariatric surgery
- physical activity
- extracorporeal membrane oxygenation
- weight gain
- roux en y gastric bypass
- patient reported
- gastric bypass