Detection of α-defensin in synovial fluids by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry as an innovative and cost-effective assay for improved definition of periprosthetic joint infections.

Andrea PetruccaIolanda SantinoGiovanna GentileDaniele MazzaEdoardo VigliettaRaffaele IorioMaurizio SimmacoAndrea FerrettiMarina Borro

Published in: Rapid communications in mass spectrometry : RCM (2021)

The reported MALDI-TOF MS assay was able to detect and differentiate HNPs in SF samples and showed a slightly better diagnostic accuracy than the Synovasure assay.

Keyphrases

high throughput
mass spectrometry
total hip
loop mediated isothermal amplification
single cell
total knee arthroplasty
real time pcr
sensitive detection