Subcutaneous Methylnaltrexone for Treatment of Opioid-Induced Constipation in Cancer versus Noncancer Patients: An Analysis of Efficacy and Safety Variables from Two Studies.
Bruce H ChamberlainMichelle RhinerNeal E SlatkinNancy StamblerRobert J IsraelPublished in: Journal of pain research (2021)
Methylnaltrexone reduced RFL time in advanced-illness patients with and without active cancer, while maintaining pain control with opioid treatment despite higher baseline opioid use among cancer patients.