MicroRNAs are necessary for the emergence of Purkinje cell identity.

Norjin ZolbootYao XiaoJessica X DuMarwan M GhanemSu Yeun ChoiMiranda J JunnFederico ZampaZeyi HuangNorjin ZolbootGiordano Lippi

Published in: bioRxiv : the preprint server for biology (2023)

Fast miRNA loss-of-function with T6B impairs postnatal Purkinje cell developmentReversible T6B reveals critical miRNA windows for dendritogenesis and synaptogenesisConditional Spy3-Ago2 mouse line enables miRNA-target network mapping in rare cellsPurkinje cell-enriched miR-206 regulates its unique dendritic and synaptic morphology.

Keyphrases

single cell
cell therapy
long non coding rna
stem cells
high resolution
preterm infants
mass spectrometry