Tissue Compliance and Intracranial Pressure Responses to Large Intracerebral Hemorrhage in Young and Aged Spontaneously Hypertensive Rats.
Cassandra M WilkinsonAnna C J KalisvaartTiffany F C KungAshley H AbrahartElmira KhiabaniFrederick ColbournePublished in: Hypertension (Dallas, Tex. : 1979) (2023)
Aged SHRs show considerable capacity for tissue compliance following ICH and seem to rely on such mechanisms more heavily in settings of elevated ICP. Therefore, the ICP compensation response to ICH mass effect varies across the lifespan according to risk factors such as chronic hypertension.