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EFFICACY OF INTRAVENOUS IMMUNOGLOBULIN ALONE ON CORONARY ARTERY LESION REDUCTION IN KAWASAKI DISEASE.

Ho-Chang KuoMing-Chih LinChung-Chih KaoKen-Pen WengYun DingChih-Jung ChenSheng-Ling JanKuang-Jen ChienChun-Hsiang KoChien-Yu LinWei-Te LeiLing-Sai ChangMindy Ming-Huey GuoKuender D YangKarl G SylvesterZhi HanJohn C WhitinLu TianHenry ChubbWScott R CeresnakDoff B McElhinneyHarvey J CohenXuefeng B Ling
Published in: medRxiv : the preprint server for health sciences (2024)
Comparison analysis indicated the non-inferiority between two groups with or without high-dose aspirin.Administering the standard 2 g/kg/day IVIG without high-dose aspirin (80-100 mg/kg/day) during the acute phase therapy for KD does not increase the risk of coronary artery lesions, which are a primary cause of morbidity and mortality in KD patients.Addition of high-dose aspirin during initial IVIG treatment is not statistically significant or clinically meaningful.
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