Evolutionary conserved relocation of chromatin remodeling complexes to the mitotic apparatus.

Giovanni MessinaYuri ProzzilloFrancesca Delle MonacheMaria Virginia SantopietroPatrizio Dimitri

Published in: BMC biology (2022)

Overall, our results support the existence of evolutionarily conserved diverse roles of chromatin remodeling complexes, whereby subunits of the SRCAP and p400/Tip60 complexes relocate from the interphase chromatin to the mitotic apparatus, playing moonlighting functions required for proper execution of cell division.

Keyphrases

transcription factor
genome wide
dna damage
gene expression
cell cycle
single cell
dna methylation
stem cells
cell therapy
oxidative stress
bone marrow