Neonatal amygdala microstructure mediates the relationship between gestational glycemia and offspring adiposity.
Shirong CaiIzzuddin M ArisWen Lun YuanKok Hian TanKeith M GodfreyPeter D GluckmanLynette Pei-Chi ShekYap-Seng ChongFabian YapMarielle V FortierMichael J MeaneyYung Seng LeeAnqi QiuPublished in: BMJ open diabetes research & care (2021)
In the offspring of non-obese mothers, gestational fasting glucose concentration is negatively associated with neonatal right amygdala FA and positively associated with childhood adiposity. Neonatal right amygdala FA may be a potential mediator between maternal glycemia and childhood adiposity.
Keyphrases
- weight gain
- birth weight
- insulin resistance
- functional connectivity
- high fat diet
- body mass index
- resting state
- prefrontal cortex
- adipose tissue
- pregnant women
- weight loss
- blood glucose
- metabolic syndrome
- pregnancy outcomes
- temporal lobe epilepsy
- type diabetes
- early life
- white matter
- blood pressure
- stress induced
- childhood cancer
- climate change
- obese patients
- gestational age
- human health