Diagnostic accuracy of 68 Ga-prostate-specific membrane antigen (PSMA) positron-emission tomography (PET) and multiparametric (mp)MRI to detect intermediate-grade intra-prostatic prostate cancer using whole-mount pathology: impact of the addition of 68 Ga-PSMA PET to mpMRI.
Matthijs J V ScheltemaJohn I ChangPhillip D StrickerPim J van LeeuwenQuoc A NguyenBao HoWarick DelpradoJonathan LeeJames E ThompsonThomas CusickAlette S SpriensmaAmila R SiriwardanaCarlo YuenRaji KoonerGeorge HrubyGordon O'NeillLouise EmmettPublished in: BJU international (2019)
PSMA-PET is accurate in detecting segments containing intermediate-grade intra-prostatic PCa (ISUP grade ≥ 2), compared with and complementary to mpMRI. By contrast the detection rate for ISUP grade 1 disease for both PSMA-PET and mpMRI was low.