Assessment of sperm chromosomal abnormalities using fluorescence in situ hybridization (FISH): implications for reproductive potential.
Francesca Paola LuongoEugenia AnnunziFrancesca GirolamoGiuseppe BelmonteRosetta PonchiaPaola PiomboniAlice LuddiPublished in: Journal of assisted reproduction and genetics (2024)
Our results showed the correlation between altered seminal parameters and numerical chromosomal abnormalities, confirming that sperm FISH analysis could be an additional clinical tool to assess reproductive potential in infertile males. Moreover, our results point to the importance of updating the normality ranges for detecting chromosomal aneuploidies using FISH.