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Joint patient and clinician priority setting to identify 10 key research questions regarding the long-term sequelae of COVID-19.

Linzy Houchen-WolloffKrisnah PoinasamyKate HolmesMaryrose TarpeyClaire HastieKelly RaihaniNatalie RogersNikki SmithDawn AdamsPaul BurgessJean ClarkClare CranageMahadev DesaiNicola GearyRhyan GillJitendra MangwaniLily StauntonColin BerryCharlotte Emma BoltonTrudie ChalderJames ChalmersAnthony De SoyzaOmer ElneimaJohn GeddesSimon HellerLing-Pei HoJoseph JacobHamish McAuleyAarti ParmarJennifer Kathleen QuintBetty RamanMatthew RowlandAmisha SingapuriSally J SinghDavid ThomasMark R ToshnerLouise V WainAlex Robert HorsleyMichael MarksChristopher E BrightlingRachael Andrea Evans
Published in: Thorax (2022)
Given the large numbers of people infected and high rates of ongoing morbidity, research is clearly required to address the needs of adult survivors of COVID-19 living with ongoing symptoms (long COVID). To help direct resource and research efforts, we completed a research prioritisation process incorporating views from adults with ongoing symptoms of COVID-19, carers, clinicians and clinical researchers. The final top 10 research questions were agreed at an independently mediated workshop and included: identifying underlying mechanisms of long COVID, establishing diagnostic tools, understanding trajectory of recovery and evaluating the role of interventions both during the acute and persistent phases of the illness.
Keyphrases
  • coronavirus disease
  • sars cov
  • respiratory syndrome coronavirus
  • liver failure
  • case report
  • intensive care unit
  • quality improvement