Defective interferon-gamma production is common in chronic pulmonary aspergillosis.

Stefano A P ColomboRola HashadDavid W DenningDinakantha S KumararatneLourdes Ceron-GutierrezGabriela Barcenas-MoralesAndrew S MacDonaldChris HarrisRainer DoffingerChris Kosmidis

Published in: The Journal of infectious diseases (2021)

Patients with CPA show impaired IFNγ production in peripheral blood in response to stimuli. Defective IFNγ production ability correlates with worse outcomes. Immunotherapy with IFNγ could be beneficial for patients showing impaired IFNγ production in CPA.

Keyphrases

dendritic cells
immune response
peripheral blood
end stage renal disease
ejection fraction
chronic kidney disease
peritoneal dialysis
prognostic factors
type diabetes
metabolic syndrome
adipose tissue
insulin resistance
skeletal muscle
drug induced