Association between ABCC2 polymorphism and hematological toxicity in patients with esophageal cancer receiving platinum plus 5-fluorouracil therapy.

Kazuma FujitaSatoru MotoyamaYusuke SatoAkiyuki WakitaYushi NagakiYoshihiro MinamiyaMasatomo Miura

Published in: Esophagus : official journal of the Japan Esophageal Society (2021)

We determined that ABCC2 -24C>T is significantly associated with grade 3-4 hematological toxicity after platinum plus 5-FU therapy. These findings might contribute to improved treatment strategies for patients with esophageal cancer.

Keyphrases

oxidative stress
stem cells
mesenchymal stem cells
cell therapy
bone marrow
oxide nanoparticles