Isolation of bioactive compounds from medicinal plants used in traditional medicine: Rautandiol B, a potential lead compound against Plasmodium falciparum.
Christiana J DawurungMinh T H NguyenJutharat PengonKanchana DokladdaRatchanu BunyongRoonglawan RattanajakSumalee KamchonwongpaisanPhuong T M NguyenStephen G PynePublished in: BMC complementary medicine and therapies (2021)
These studies have led to the identification of lead compounds with potential for future drug development, including Rautandiol B, as a potential lead compound against Plasmodium falciparum. The relatively higher inhibitory activities of the crude extracts against AG and AA over their isolated components could be due to the synergistic effects between their phytochemical components. These crude extracts could potentially serve as alternative inhibitors of AG and AA and as therapeutics for diabetes.