The glial cell's role in antinociceptive differential effects of oxytocin upon female and male rats.

Ana B Salinas-AbarcaFrancisco G Vázquez-CuevasAdriana González-GallardoGuadalupe Martínez-LorenzanaAbimael González-HernándezMiguel Condés-Lara

Published in: European journal of pain (London, England) (2022)

Oxytocin is a molecule that emerges as a potent analgesic in preclinical and clinical studies. We investigated the contribution of glia to the response of oxytocin-induced analgesia and how sex influences in this response show that different strategies are required to treat pain in men and women, and that oxytocin could be used preferentially to treat pain with a significant inflammatory component in men.

Keyphrases

neuropathic pain
pain management
chronic pain
anti inflammatory
cell therapy
single cell
spinal cord injury
postoperative pain
oxidative stress
high glucose
ultrasound guided
mass spectrometry
atomic force microscopy
high resolution