Osteomodulin attenuates smooth muscle cell osteogenic transition in vascular calcification.

Nikolaos T SkenterisTill SeimeAnna WitaspEva KarlöfGrzegorz B WasilewskiMarina A HeuschkelArmand M G JaminonLoureen OduorRobert DzhanaevMalin KronqvistMariette LengquistFrederique E C M PeetersMagnus SöderbergRebecka HultgrenJoy RoyLars MaegdefesselHildur ArnardottirEva BengtssonIsabel GoncalvesThomas QuertermousClaudia GoettschPeter StenvinkelLeon J SchurgersLjubica Matic

Published in: Clinical and translational medicine (2022)

regions of calcified cardiovascular tissues, induced by pro-inflammatory and pro-osteogenic stimuli, while the presence of OMD in extracellular environment attenuated SMC calcification.

Keyphrases

smooth muscle
mesenchymal stem cells
bone marrow
chronic kidney disease
cell therapy
single cell
gene expression
stem cells