Association between mucosal barrier disruption by Pseudomonas aeruginosa exoproteins and asthma in patients with chronic rhinosinusitis.

Jannatul Ferdoush Tuli Mahnaz RamezanpourClare CooksleyAlkis James PsaltisPeter-John WormaldSarah Vreugde

Published in: Allergy (2021)

Exoproteins from planktonic P. aeruginosa clinical isolates from asthmatic CRS patients have detrimental effects on the mucosal barrier and induce IL-6 production potentially contributing to the mucosal inflammation in CRS patients.

Keyphrases

end stage renal disease
pseudomonas aeruginosa
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
oxidative stress
cystic fibrosis
chronic obstructive pulmonary disease
escherichia coli
lung function
staphylococcus aureus
ulcerative colitis
air pollution
acinetobacter baumannii