Occlusion of the infarct-related coronary artery presenting as acute coronary syndrome with and without ST-elevation: impact of inflammation and outcomes in a real-world prospective cohort.
Francesco BrunoBoris AdjibodouSlayman ObeidSimon KralerFlorian A WenzlM Majid AkhtarAndrea DenegriMarco RoffiOlivier MüllerArnold Von EckardsteinLorenz RäberChristian TemplinThomas F Lüschernull nullPublished in: European heart journal. Quality of care & clinical outcomes (2023)
In NSTE-ACS, both LCx and RCA involvement was associated with TCO at angiography despite the absence of ST-segment elevation. Involvement of the LCx, but not the LAD or RCA, as the IRA represented an independent predictor of MACE during 1-year follow-up. Hs-CRP, lymphocyte and neutrophil counts were independent predictors of total IRA occlusion suggesting a possible role of systemic inflammation in the detection of TCO irrespective of ECG presentation.
Keyphrases
- acute coronary syndrome
- coronary artery
- percutaneous coronary intervention
- antiplatelet therapy
- peripheral blood
- oxidative stress
- optical coherence tomography
- pulmonary artery
- acute myocardial infarction
- computed tomography
- heart rate variability
- heart rate
- loop mediated isothermal amplification
- case report
- type diabetes
- metabolic syndrome
- real time pcr
- atrial fibrillation
- drug induced