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Androgen receptor and MYC transcriptomes are equilibrated in multilayer regulatory circuitries in prostate cancer.

Bin FuLiyang WangTianwei JiaZhao WeiNuosu NamaJiaqian LiangXinghua LiaoXiaMing LiuYanfei GaoXiaoqiang LiuRaymond S MaoKeshan WangJu GuoShaoyong S Chen
Published in: The Prostate (2023)
Together, our findings stratified AR-MYC interactions that are extensively wired and intricately organized to compensate for essential PCa transcriptional programs and neutralize excessive signaling.
Keyphrases
  • transcription factor
  • prostate cancer
  • radical prostatectomy
  • multidrug resistant
  • public health
  • weight gain
  • single cell
  • gene expression
  • body mass index
  • heat shock
  • oxidative stress