Investigation of the gut microbiome, bile acid composition and host immunoinflammatory response in a model of azoxymethane-induced colon cancer at discrete timepoints.
J M KeaneC J WalshP CroninK BakerS MelgarP D CotterS A JoyceC G M GahanAileen HoustonNiall P HylandPublished in: British journal of cancer (2022)
The observed changes precede host hyperplastic transformation and may represent early therapeutic targets for the prevention or management of CRC at specific timepoints in the tumorigenic process.