Characterization of a Carbapenem-Resistant BKC-1-Producing Clinical Isolate Belonging to the Pseudomonas putida Group from Brazil.
Felipe Alberto-LeiCarolina Silva NodariAna Paula StrelingFrancisco O Bessa-NetoAndré V SiqueiraRodrigo CayôAna Cristina GalesPublished in: Antimicrobial agents and chemotherapy (2022)
Since its first report, the class A Brazilian Klebsiella carbapenemase (BKC) has been detected only among Enterobacterales isolates from Brazilian hospitals. In this study, we characterized a multidrug-resistant Pseudomonas juntendi clinical isolate and identified a 43.3-kb plasmid carrying bla BKC-1 and a class 1 integron (In 1996 ) containing the arr-2 , qnrVC1 , dfrA21 , and aac(6')-Ib' gene cassettes. Our results confirm the ability of Pseudomonas putida group isolates to acquire antimicrobial resistance determinants and further act as resistance reservoirs.