Cross-genetic determination of maternal and neonatal immune mediators during pregnancy.

Michela TragliaLisa A CroenKaren L JonesLuke S HeuerRobert YolkenMartin KharraziGerald N DeLorenzePaul AshwoodJudy Van de WaterLauren A Weiss

Published in: Genome medicine (2018)

Our results suggest that maternal and fetal genetic variation influences the immune system during pregnancy and at birth via distinct mechanisms and that a better understanding of immune factor determinants in early development may shed light on risk factors for developmental disorders.

Keyphrases

pregnancy outcomes
birth weight
gestational age
pregnant women
solid phase extraction
gene expression
weight loss