Effects of extremely preterm birth on cytokine and chemokine responses induced by T-cell activation during infancy.

Dhanapal Govindaraj Georg Bach JensenKhaleda Rahman QaziEva Sverremark-EkströmThomas AbrahamssonMaria C Jenmalm

Published in: Clinical & translational immunology (2024)

Immune mediators induced by T-cell activation in EPT infants were mainly reduced at D14 and Th2 skewed compared to those in FT infants, but mostly recovered at Gw36, indicating immune maturation. Increased proinflammatory responses at D28 may be related to the heightened risk of severe immune-associated complications seen in EPT infants.

Keyphrases

preterm birth
low birth weight
gestational age
risk factors
early onset
body mass index
physical activity
preterm infants
drug induced
weight loss