Bone defect treatment: does the type and properties of the spacer affect the induction of Masquelet membrane? Evidence today.
Emmanouil LiodakisVassilis P GiannoudisStephan SehmischAnimesh JhaPeter V GiannoudisPublished in: European journal of trauma and emergency surgery : official publication of the European Trauma Society (2022)
Membranes induced by smooth PMMA spacers loaded with low concentrations of antibiotics showed powerful osteogenic properties. Other materials such as Polypropylene or Calcium sulfate can also be used with good results. Despite current recommendation to perform the second stage operation in 4-8 weeks, membranes older than 8 weeks seem to have similar regenerative capacities to younger ones.