Contribution of alpha-synuclein pathology to cerebral glucose metabolism in patients with amnestic MCI.

Markus OttoGaregin ArajyanEric M ReimanMarkus OttoChristopher M Weisenull null

Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)

αSyn pathology can be detected in vivo by CSF αSyn SAA. We investigated the FDG PET pattern in aMCI patients with CSF αSyn SAA positivity. αSyn+ aMCI showed a marked brain hypometabolism in AD and DLB typical regions.

Keyphrases

mild cognitive impairment
pet ct
positron emission tomography
pet imaging
computed tomography
white matter
cerebral ischemia
atomic force microscopy
blood brain barrier
high resolution
brain injury
high speed