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Maintenance or Discontinuation of Antidepressants in Primary Care.

Gemma LewisLouise MarstonLarisa DuffyNick FreemantleSimon GilbodyRachael HunterTony KendrickDavid KesslerDee ManginMichael KingPaul LanhamMichael MooreIrwin NazarethNicola WilesFaye BaconMolly BirdSally BrabynAlison BurnsCaroline S ClarkeAnna HuntJodi PervinGlyn Lewis
Published in: The New England journal of medicine (2021)
Among patients in primary care practices who felt well enough to discontinue antidepressant therapy, those who were assigned to stop their medication had a higher risk of relapse of depression by 52 weeks than those who were assigned to maintain their current therapy. (Funded by the National Institute for Health Research; ANTLER ISRCTN number, ISRCTN15969819.).
Keyphrases
  • primary care
  • major depressive disorder
  • healthcare
  • depressive symptoms
  • quality improvement
  • mesenchymal stem cells
  • sleep quality
  • bipolar disorder
  • bone marrow
  • physical activity