In Vivo Evaluation of Near-Infrared Fluorescent Probe for TIM3 Targeting in Mouse Glioma.

Michael ZhangQuan ZhouChinghsin HuangCarmel T ChanWei WuGordon LiMichael LimSanjiv S GambhirHeike E Daldrup-Link

Published in: Molecular imaging and biology (2021)

We propose fluorescent imaging of immune cell imaging as a potential strategy for monitoring and localizing immunologically relevant foci in the setting of brain tumors. Alternative markers and target validation will further clarify the temporal relationship of immunosuppressive effector cells throughout glioma resistance.

Keyphrases

fluorescent probe
living cells
high resolution
induced apoptosis
cell cycle arrest
quantum dots
dendritic cells
regulatory t cells
signaling pathway
immune response
mass spectrometry
risk assessment
single molecule
cell proliferation
cell death
pi k akt