Cognitive functioning following discontinuation of antipsychotic medication. A naturalistic sub-group analysis from the OPUS II trial.
Nikolai AlbertLasse RandersKelly AllottHeidi Dorthe JensenMarianne MelauCarsten HjorthøjMerete NordentoftPublished in: Psychological medicine (2018)
Due to the naturalistic design, we cannot conclude on the direction of the relationship between antipsychotics and cognition. There is no evidence that discontinuation of medication had a negative effect on cognitive functioning. Rather, we found that that discontinuation of medication was associated with better cognitive functioning.