Relevance of polymorphisms in MC4R and BDNF in short normal stature.

Nikolas HerrfurthAnna-Lena VolckmarTriinu PetersGunnar KleinauAnne MüllerCigdem CetindagLaura SchonnopManuel FöckerAstrid DempfleStefan A WudyStruan F A GrantThomas ReinehrDiana L CousminerJohannes HebebrandHeike BiebermannAnke Hinney

Published in: BMC pediatrics (2018)

Taken together, although genes of the leptinergic-melanocortinergic system are important for normal growth, our data do not support the involvement of rare mutations in LEP, MC4R, MRAP2 or BDNF in short normal stature.

Keyphrases

genome wide
big data
dna methylation
transcription factor
data analysis