Inhibition of transglutaminase activity in periodontitis rescues periodontal ligament collagen content and architecture.

Emilie Moore RossetJessica Trombetta-eSilvaGlenn HepferPeng ChenHai YaoAmy D Bradshaw

Published in: Journal of periodontal research (2019)

These studies support a role of TG in regulating collagen fiber assembly and suggest that strategies to inhibit TG activity in disease might contribute to restoration of PDL tissue integrity.

Keyphrases

wound healing
tissue engineering
mouse model