Paediatric follicular thyroid carcinoma - indolent cancer with low prevalence of RAS mutations and absence of PAX8-PPARG fusion in a Japanese population.

Huy Gia VuongTetsuo KondoNaoki OishiTadao NakazawaKunio MochizukiAkira MiyauchiMitsuyoshi HirokawaRyohei Katoh

Published in: Histopathology (2017)

Paediatric FTCs are indolent in clinical course in spite of their large tumour size and have a distinct genetic background. RAS mutations and PAX8-PPARG fusions may not play major roles in the tumorigenesis of paediatric FTCs.

Keyphrases

intensive care unit
emergency department
papillary thyroid
wild type
risk factors
hodgkin lymphoma
genome wide
squamous cell
squamous cell carcinoma
gene expression
dna methylation
childhood cancer