Combination of Antidepressants and Antipsychotics as A Novel Treatment Option for Psychosis in Alzheimer's Disease.

Peihao FanLang ZengYing DingJulia KoflerJonathan SilversteinJoshua KrivinkoRobert A SweetLirong Wang

Published in: medRxiv : the preprint server for health sciences (2023)

Our proposed combinations of antipsychotics and antidepressants therapy showed a strong superiority over current antipsychotics treatment for AD+P. The observed beneficial effects can be further strengthened by optimizing drug-pair selection based on our systems pharmacology analysis.

Keyphrases

major depressive disorder
emergency department
combination therapy
drug induced
cell therapy
adverse drug