Robust Underwater Adhesives Based on Dynamic Hydrophilic and Hydrophobic Moieties to Diverse Surfaces.

Underwater adhesives (UAs) have promising applications in diverse areas. However, traditional UAs have several drawbacks such as weak and irreversible adhesion behaviors as well as poor performance in biological environments. To address these challenges, we engineered a novel synthetic adhesive based on dynamic hydrophilic and hydrophobic moieties, which shows very strong underwater adhesion strength (30-110 kPa) and debonding energy (20-100 J/m2) to diverse substrates. Interestingly, the UAs could also be switched reversibly and repeatedly by the dynamic exchange of hydrophilic and hydrophobic moieties under alternating temperatures. We also demonstrate the versatile functions and practical value of the UAs for clinical applications as tissue sealants and hemostatic dressing in emergency rescue operations. This general and efficient strategy may be generalized to develop additional next generation UAs for many emerging technological and medical applications.