Clinical and genetic insights into non-compaction: a meta-analysis and systematic review on 7598 individuals.

Elham KayvanpourFarbod Sedaghat-HamedaniWeng-Tein GiOguz Firat TugrulAli AmrJan HaasFeng ZhuPhilipp EhlermannLorenz UhlmannHugo A KatusBenjamin Meder

Published in: Clinical research in cardiology : official journal of the German Cardiac Society (2019)

The summarized data indicate that non-compaction may lead to unfavorable outcome in different cardiomyopathy entities. The presence of key features in a multimodal diagnostic approach could distinguish between benign morphological trait and manifest cardiomyopathy.

Keyphrases

systematic review
heart failure
genome wide
meta analyses
electronic health record
big data
pain management
copy number
dna methylation