The production of a recombinant tandem single chain fragment variable capable of binding prolamins triggering celiac disease.

Britta EggenreichElke ScholzDavid Johannes WurmFlorian ForsterOliver Spadiut

Published in: BMC biotechnology (2018)

The high binding specificity of tscFv towards prolamin-containing grains makes this novel molecule a valuable candidate to support patients suffering from CD in the future.

Keyphrases

celiac disease
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
patient reported outcomes
current status
patient reported