Association between patient age, microcirculation, and coronary stenosis assessment with fractional flow reserve and instantaneous wave-free ratio.
Hernán Mejía-RenteríaDaniel FariaJoo-Myung LeeSeung-Hun LeeJi-Hyun JungJoon-Hyung DohChang-Wook NamEun-Seok ShinMasahiro HoshinoTomoyo SugiyamaYoshihisa KanajiNieves GonzaloTsunekazu KakutaBon-Kwon KooJavier EscanedPublished in: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2022)
FFR values increased progressively with patient age, potentially associated with age-related changes in the coronary microcirculation. Conversely, iFR values remained unchanged across the patient age spectrum. In ≥60 years old patients with revascularisation deferral based on FFR, both abnormal iFR and CFR values were associated with worse long-term patient outcomes.