K-RAS Associated Gene-Mutation-Based Algorithm for Prediction of Treatment Response of Patients with Subtypes of Breast Cancer and Especially Triple-Negative Cancer.
Heather JohnsonAmjad AliXuhui ZhangTianyan WangAthanasios SimoulisAnette Gjörloff WingrenJenny L PerssonPublished in: Cancers (2022)
The novel 12-Gene algorithm based on multitude gene-mutation profiles identified through ML has a potential to predict breast cancer treatment response to therapies, especially in triple-negative subgroups patients, which may assist personalized therapies and reduce mortality.
Keyphrases
- end stage renal disease
- machine learning
- deep learning
- newly diagnosed
- ejection fraction
- chronic kidney disease
- peritoneal dialysis
- papillary thyroid
- prognostic factors
- cardiovascular events
- squamous cell carcinoma
- genome wide
- cardiovascular disease
- copy number
- type diabetes
- coronary artery disease
- squamous cell
- patient reported outcomes
- human health
- patient reported