Time trends in human papillomavirus prevalence and genotype distribution in vulvar carcinoma in Norway.
Christin Julia Meltzer-GunnesAgnes Kathrine LieChristine Genevieve Monceyron JonassenAnbjørg RangbergCamilla Furlund NystrandMilada Cvancarova SmåstuenIngvild VistadPublished in: Acta obstetricia et gynecologica Scandinavica (2023)
The prevalence of HPV in vulvar squamous cell carcinomas in Norway was significantly higher in 2000-2005 than in 1970-1975. The three predominant genotypes were HPV 16, 33 and 18 in both time periods. However, several other HPV genotypes have emerged over the last decades. HPV-positivity was associated with better overall survival.