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2-Methoxy-1,4-Naphthoquinone (MNQ) Inhibits Glucose Uptake and Lactate Production in Triple-Negative Breast Cancer Cells.

Syukriyah Mat DaudNik Soriani YaacobAgustine Nengsih Fauzi
Published in: Asian Pacific journal of cancer prevention : APJCP (2021)
Our findings indicate the ability of MNQ to inhibit the glycolytic activities as well as glycolysis-related molecules in MDA-MB-231 cells, suggesting the potential of MNQ to be further developed as an effective anticancer agent against TNBC cells.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • breast cancer cells
  • endoplasmic reticulum stress
  • type diabetes
  • pi k akt
  • adipose tissue
  • skeletal muscle
  • weight loss